Helicobacter was the head of the cloning industry, and his profession was vivisection on Humans in order to study them. Apparently, Helicobacter was the only cloner who used anesthetics and the one who kept prime human specimens to experiment on. He was the Emperor Meningitis' right-hand man (as opposed to Orthopox who was the right-hand). Helicobacter also had Nexos that served as security drones and enforcers. Helicobacter was lured to Endometriosis by Crypto when Crypto Body Snatched a worker and was killed after that.
In Destroy All Humans! Path of the Furon, Helicobacter was shown briefly in the second to last mission. His full description was shown to have one mechanical left eye and one organic green eye. Helicobacter was often hunched over with two long mechanical arms on his back and was equipped with a syringe on his left arm.
- Helicobacter was named after the Helicobacter Pylori.