Destroy All Humans![]
Be aware that these cheats apply to the original game only.
PS4/XBOX ONE
The following Cheat Codes must be activated in the pause menu while holding L2 or the L respectively.
Note: On xbox one and 360 versions LB replaces White and RB replaces Black
Bullet Proof Crypto[]
Infinite Health
- Square, Circle, left, left, Circle Square (Playstation Versions)
- X, Y, Left, Left, Y, X. (Xbox Versions)
Ammo-A-Plenty[]
Infinite Ammo
- Left, Circle, R2, Right, R1, Square (PlayStation Versions)
- Left, Y, White, Right, Black, X (Xbox Versions)
Deep Thinker[]
Infinite Concentration
- R1, R2, Circle, Right, R2, Circle (Playstation Versions)
- Black, White, Y, Right, White, Y (Xbox Versions)
Aware Like A Fox[]
Full Alert Level
- R-□-R2-R1-R-R2 (Playstation Versions)
- Right, X, White, Black, Right, White, (Xbox Versions)
Nobody Love You[]
Resets Alert Level
- R2, Right, R2, R1, Square, Right (Playstation Versions)
- White, Right, White, Black, X, Right, (Xbox Versions)
The Following Codes must be entered on the mothership while holding L2 or L respectively.
Key to Orthopox's lab[]
All Upgrades Unlocked
- Square, Circle, Left, Left, Circle, Square (PlayStation Versions)
- X, Y, Left, Left, Y ,X (Xbox Versions)
MMM. . . Brains![]
Extra DNA
- R1, R1, R2, R2, Left, Right, Left, Right, R2, R1 (PlayStation Versions)
- Black, Black, White, White, Left, Right, Left, Right, White, Black. (Xbox Versions)
Destroy All Humans! 2 Reprobed[]
The following Cheat Codes must be activated via entering the codes with the weapon wheel up and closing it once inputted or holding ALT while inputting on PC
Salad Days[]
Also works in the original.
- A, X, Y, B, X, B, Y, A, A (Xbox Series version)
- X, Square, Triangle, Circle, Square, Circle, Triangle, X, X (PS5 version)
- S, A, W, D, A, D, W, S, S (PC Version)
Note: Entering the code the way it's shown above will show Salad Days with Pox and Crypto in it's original form. Entering it backwards will show a remade version
Invincibility[]
- RT, LT, A, Right D-pad (Xbox Series version)
- R2, L2, X, Right D-pad (PS5 version)
- Right Mouse Button, Left Mouse Button, S, D/Right Arrow (PC Version)
Infinite Ammo[]
- A, B, X, X, Y (Xbox Series version)
- X, Circle, Square, Square, Triangle (PS5 version)
- S, D, A, A, W (PC version)
Infinite Bodysnatch[]
- X, B, X, B (Xbox Series version)
- Square, Circle, Square, Circle (PS5 version)
- A, D, A, D (PC version)
Head-O-Ween[]
Replaces dropped brains with a pumpkin
- Y, Y, A, A (Xbox Series version)
- Triangle, Triangle, X, X (PS5 version)
- W, W, S, S (PC version)
Spanksgiving[]
Replaces dropped brains with turkeys
- Y, Y, B, B (Xbox Series version)
- Triangle, Triangle, Circle, Circle (PS5 version)
- W, W, D, D (PC version)
Spanksgiving Off[]
Replaces dropped brains with easter eggs (Mistitled cheat at time of finding; may be corrected)
- Y, X, A, A (Xbox Series version)
- Triangle, Square, X, X (PS5 version)
- W, A, S, S (PC version)
CortXmas[]
Replaces dropped brains with Christmas Presents
- Y, Y, X, X (Xbox Series version)
- Triangle, Triangle, Square, Square (PS5 version)
- W, W, A, A (PC version)
Max Alert[]
Raises the alert level to max
- A, Y, Y, Y (Xbox Series version)
- X, Triangle, Triangle, Triangle (PS5 version)
- S, W, W, W (PC version)
All Clear[]
Automatically clear the alert level
- Y, A, A, A (Xbox Series version)
- Triangle, X, X, X (PS5 version)
- W, S, S, S (PC version)
DESTROY ALL HUMANS![]
Kills humans/enemies and destroys vehicles that you are aiming at
- Y, A, B, X, A (Xbox Series version)
- Triangle, X, Circle, Square, X (PS5 version)
- W, S, D, A, S (PC version)
All Upgrades[]
Toggles weapon upgrades, Skate upgrades don't seem to be affected, or weapons received after inputting. Will revert after a loading screen.
- A, X, A, B, A, Y, Y, Y (Xbox Series version)
- S, A, S, D, S, W, W, W (PC version)
Have any more cheat codes across the 4 games? Submit them here!